The aim of this study is to find out the preferences of students (150) in the first year of the study of the Preschool and Primary Education programme. The data was collected using a questionnaire in the first seminar focusing on science content (a course called Science Propaedeutics) to determine the preferences of pre-service teachers. The aim was to find out the (un)popularity of STEM (Science, Technology, Engineering, Mathematics) education covering the subjects of Biology, Physics, Mathematics, Technology and Chemistry in Slovakia. The results showed that students are interested in science education. The findings also showed that students prefer more biological topics (humans and plants) and less physics, chemistry, and mathematics. They also preferred topics that they knew from everyday life. The results revealed a negative correlation between students' concerns about teaching science in their future practice and their interest in science education. We found it necessary to connect the topics to everyday life and avoid mathematical calculations. So we can increase their interest in these areas/issues in the Science Propaedeutics course.